Quality Control

Eight checks between synthesis and your laboratory bench

We treat the analytical chain as seriously as the synthesis. Every batch — without exception — is verified by an independent third-party laboratory, cold-chain shipped, and traceable from the manufacturing record to the vial label in your hand.

01
Solid-phase peptide synthesis

Lyophilised peptide produced under controlled humidity and temperature in a partner facility audited for cGMP-compatible practice.

02
Reversed-phase HPLC purity test

UV detection at 214 nm. Single-peak integration. Any batch below 98% purity is rejected before it leaves the synthesis facility.

03
LC-MS identity confirmation

Liquid chromatography coupled with mass spectrometry confirms the parent ion matches the theoretical molecular weight within instrument tolerance.

04
Independent Certificate of Analysis

An accredited third-party lab — separate from the synthesis facility — re-runs HPLC and LC-MS. The COA they sign is what we publish, not the manufacturer's internal data.

05
Batch traceability

Every vial carries a unique batch number traceable to the synthesis lot, the COA file ID, the test date and the principal chemist's signature.

06
Tamper-evident, double-sealed vials

Crimped aluminium cap over a butyl rubber stopper, with a tamper band that breaks visibly on first opening. Lyophilised cake inspected visually before shipment.

07
Cold-chain stocked and packed

Vials kept at 2–8 °C in a temperature-logged store. Insulated packaging with phase-change gel packs sized to the courier transit time.

08
Tracked courier with temperature log

UK-tracked next-day courier. Each shipment includes a logged temperature record. If the cold chain is breached in transit, we replace the vial — no questions.

Independent COA pass rate
100%
Below 98% purity = rejected
Average reported purity
≥ 99%
HPLC at 214 nm
Cold-chain integrity
99.8%
Replaced if breached
COA promise

If a Certificate of Analysis cannot be produced for a batch you have purchased, or the COA on file fails to match the batch number printed on the vial, we will refund the order in full. No question, no admin process — email the order code and the batch number to research@spherespeptides.com.